Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285431 | 0.85 | EPHX2 (0.52) | CTSSCTSKPPARA | |
| SCHEMBL11892918 | 0.85 | HDAC1 (0.53) | CTSSCTSKCTSBAOC3HDAC1 | |
| SCHEMBL11892929 | 0.83 | AOC3 (0.49) | CTSSCTSKCTSBAOC3HDAC1 | |
| SCHEMBL11356388 | 0.82 | CTSB (0.48) | CTSSCTSKCTSBAOC3CTSL | |
| SCHEMBL27118264 | 0.82 | HDAC1 (0.48) | CTSSCTSKCTSBAOC3HDAC1 | |
| SCHEMBL30504293 | 0.81 | HDAC1 (0.56) | CTSSCTSKCTSBAOC3HDAC1 | |
| SCHEMBL18664430 | 0.80 | PPARA (0.56) | CTSSCTSKHDAC1PPARA | |
| SCHEMBL352314 | 0.79 | ERCC1 (0.52) | CTSSCTSKCTSBBRD4CREBBP | |
| SCHEMBL18664426 | 0.79 | HDAC1 (0.60) | CTSSCTSKCTSBAOC3HDAC1 | |
| SCHEMBL11892904 | 0.79 | AOC3 (0.52) | CTSSCTSKCTSBAOC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-A1 | GLYCINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-07-25 | — | — | EP | disclosed |