Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892923 | 0.86 | PTPN1 (0.47) | AOC3HDAC1NAMPTPTPN1CYP17A1 | |
| SCHEMBL11892918 | 0.85 | HDAC1 (0.53) | AOC3HDAC1CTSBCTSSCTSK | |
| SCHEMBL11892924 | 0.84 | NAMPT (0.52) | AOC3HDAC1NAMPTROCK2NPFFR1 | |
| SCHEMBL11892915 | 0.83 | CTSS (0.50) | AOC3HDAC1CTSBCTSSCTSK | |
| SCHEMBL11360023 | 0.82 | AOC3 (0.69) | AOC3MAPK14 | |
| SCHEMBL27118264 | 0.82 | HDAC1 (0.48) | AOC3HDAC1CTSBCTSSCTSK | |
| SCHEMBL30504293 | 0.81 | HDAC1 (0.56) | AOC3HDAC1CTSBCTSSCTSK | |
| SCHEMBL3507808 | 0.79 | BRD4 (0.53) | NAMPTPTPN1BRD4GLSROCK2 | |
| SCHEMBL18664426 | 0.79 | HDAC1 (0.60) | AOC3HDAC1CTSBCTSSCTSK | |
| SCHEMBL11892904 | 0.79 | AOC3 (0.52) | AOC3HDAC1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-A1 | GLYCINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-07-25 | — | — | EP | disclosed |