SCHEMBL1189519

SCHEMBL1189519

O=C(CN1CCNCC1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
SIGMAR1 Q99720 2/20 0.56
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
POLB P06746 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51
USP2 O75604 1/20 0.50
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50
KDR P35968 1/20 0.48
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48
KCNH2 Q12809 1/20 0.48
KMT2A Q03164 3/20 0.47
EGFR P00533 1/20 0.47
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12367170 0.98 ALDH1A1 (0.61) ALDH1A1SIGMAR1SLC6A4SLC6A3POLB
Hydrochloric Acid SCHEMBL1763146 0.98 ALDH1A1 (0.61) ALDH1A1SIGMAR1SLC6A4SLC6A3POLB
SCHEMBL24672685 0.98 ALDH1A1 (0.61) ALDH1A1SIGMAR1SLC6A4SLC6A3POLB
SCHEMBL6023614 0.90 RAB9A (0.55) ALDH1A1POLBCYP3A4CYP2D6MAPT
SCHEMBL4875267 0.87 ALDH1A1 (0.79) ALDH1A1SLC6A4SLC6A3POLBCYP3A4
SCHEMBL11395399 0.85 KDM5C (0.51) ALDH1A1SIGMAR1CYP2D6MAPTHSD17B10
SCHEMBL9381303 0.83 ALDH1A1 (0.69) ALDH1A1SLC6A4SLC6A3POLBCYP3A4
SCHEMBL6035088 0.83 ALDH1A1 (0.61) ALDH1A1CYP3A4CYP2D6MAPTMAPK1
SCHEMBL2616165 0.83 MEN1 (0.69) ALDH1A1CYP2D6USP2KDRKMT2A
SCHEMBL20421677 0.83 MEN1 (0.47) ALDH1A1POLBCYP3A4CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504687-A Piperazine coumarin derivative and synthetic method and application thereof 忻州师范学院 2025-02-25 CN claimed
CN-115637129-B Ultraviolet curing adhesive and preparation method thereof 烟台泰盛精化科技有限公司 2023-03-07 CN claimed
CN-115637129-A Ultraviolet curing adhesive and preparation method thereof 烟台泰盛精化科技有限公司 2023-01-24 CN claimed
CN-112939963-B Benzopyranoate derivative and synthesis method and application thereof 山西大学 2022-09-23 CN claimed
CN-111808516-B Washable ultraviolet-curable waterborne polyurethane resin and preparation method and application thereof 中国科学院福建物质结构研究所 2022-02-18 CN claimed
CN-112939963-A Benzopyranoic acid ester derivative and synthesis method and application thereof 山西大学 2021-06-11 CN claimed
CN-111808516-A Washable ultraviolet-curable waterborne polyurethane resin and preparation method and application thereof 中国科学院福建物质结构研究所 2020-10-23 CN claimed
CN-109705847-B Sulfur dioxide ratiometric fluorescent probe and synthetic method and application thereof 济南大学 2020-07-07 CN claimed
CN-111253379-A Detect SO2Ratiometric fluorescent probes, their synthesis and use 济南大学 2020-06-09 CN claimed
CN-111253356-A Coumarin-benzopyrylium salt derivative and synthesis method and application thereof 山西大学 2020-06-09 CN claimed
WO-1996022297-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1996-07-25 WO claimed
EP-0489877-B1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES UPJOHN CO (US) 1995-09-20 EP claimed
US-5302613-A Antiatheroscleroic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones THE UPJOHN COMPANY (US) 1994-04-12 US claimed
US-5252735-A Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones THE UPJOHN COMPANY (US) 1993-10-12 US claimed
EP-0525123-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. UPJOHN CO (US) 1993-02-03 EP claimed
WO-1992000290-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES THE UPJOHN COMPANY (US) 1992-01-09 WO claimed
WO-1991019707-A2 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES THE UPJOHN COMPANY (US) 1991-12-26 WO claimed
EP-0459983-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES PHARMACIA & UPJOHN COMPANY (US) 1991-12-11 EP claimed
WO-1990006921-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES THE UPJOHN COMPANY (US) 1990-06-28 WO claimed
EP-0331052-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-09-06 EP claimed