SCHEMBL12367170

SCHEMBL12367170

O=C(CN1CCNCCNCCNCC1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
SIGMAR1 Q99720 2/20 0.54
SLC6A4 P31645 2/20 0.51
SLC6A3 Q01959 2/20 0.51
POLB P06746 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP2C19 P33261 1/20 0.50
USP2 O75604 1/20 0.49
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KDR P35968 1/20 0.47
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
KCNH2 Q12809 1/20 0.47
KMT2A Q03164 3/20 0.46
EGFR P00533 1/20 0.46
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24672685 1.00 ALDH1A1 (0.61) ALDH1A1SIGMAR1SLC6A4SLC6A3POLB
SCHEMBL1189519 0.98 ALDH1A1 (0.63) ALDH1A1SIGMAR1SLC6A4SLC6A3POLB
Hydrochloric Acid SCHEMBL1763146 0.97 ALDH1A1 (0.61) ALDH1A1SIGMAR1SLC6A4SLC6A3POLB
SCHEMBL6023614 0.89 RAB9A (0.55) ALDH1A1POLBCYP3A4CYP2D6MAPT
SCHEMBL4875267 0.85 ALDH1A1 (0.79) ALDH1A1SLC6A4SLC6A3POLBCYP3A4
SCHEMBL11395399 0.84 KDM5C (0.51) ALDH1A1SIGMAR1CYP2D6MAPTHSD17B10
SCHEMBL9381303 0.82 ALDH1A1 (0.69) ALDH1A1SLC6A4SLC6A3POLBCYP3A4
SCHEMBL6035088 0.81 ALDH1A1 (0.61) ALDH1A1CYP3A4CYP2D6MAPTMAPK1
SCHEMBL20421677 0.81 MEN1 (0.47) ALDH1A1POLBCYP3A4CYP2D6MAPT
SCHEMBL2616165 0.81 MEN1 (0.69) ALDH1A1CYP2D6USP2KDRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN disclosed
US-8003078-B2 Targeted MR imaging agents BARNES-JEWISH HOSPITAL (US) 2011-08-23 US disclosed
US-20070237721-A1 TARGETED MR IMAGING AGENTS KEREOS, INC. 2007-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070237721-A1 TARGETED MR IMAGING AGENTS TSPO, ARNT, RXFP4 ALDH1A1 4832/4885SIGMAR1 290/4885SLC6A4 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.