SCHEMBL11896458

SCHEMBL11896458

C/C=C/CC(C)COC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
USP2 O75604 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
ALOX15 P16050 2/20 0.37
PTPN1 P18031 1/20 0.36
ALDH1A1 P00352 4/20 0.34
HSD17B10 Q99714 1/20 0.34
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 2/20 0.34
PRKCA P17252 1/20 0.34
CTSK P43235 2/20 0.33
HPGD P15428 1/20 0.32
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722839 1.00 LMNA (0.39) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL11896459 1.00 LMNA (0.39) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL6860272 0.81 ALOX15 (0.46) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL17203302 0.79 LMNA (0.36) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL15722853 0.79 TDP1 (0.39) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL5080054 0.79 TDP1 (0.39) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL9756912 0.78 TDP1 (0.48) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL17930146 0.77 PPARG (0.47) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL20859600 0.76 MAPT (0.50) LMNAUSP2CYP3A4MAPTSMN1; SMN2
SCHEMBL29137127 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2487149-A1 METHOD FOR PRODUCING KETONE JX Nippon Oil & Energy Corporation (JP) 2012-08-15 EP disclosed
US-20120197036-A1 METHOD FOR MANUFACTURING KETONE OSAKA UNIVERSITY (JP) 2012-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120197036-A1 METHOD FOR MANUFACTURING KETONE CBR1, CBR3, DUOX1 LMNA 4346/4885USP2 2303/4885CYP3A4 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.