Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.52 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.52 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.52 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.52 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133232 | 0.88 | ACHE (0.55) | ACHEDYRK1ACLK4CYP3A4CYP1A1 | |
| SCHEMBL11896601 | 0.85 | CYP3A4 (0.59) | ACHECYP3A4CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL29489425 | 0.82 | CYP3A4 (0.73) | ACHEDYRK1ACLK4CYP3A4CYP1A1 | |
| SCHEMBL196765 | 0.82 | CYP3A4 (0.73) | ACHEDYRK1ACLK4CYP3A4CYP1A1 | |
| SCHEMBL321834 | 0.80 | CASR (0.57) | ACHEDYRK1ACLK4CYP3A4CYP1A1 | |
| Hydrogen Sulfide SCHEMBL28640169 | 0.80 | CYP3A4 (0.70) | ACHEDYRK1ACLK4CYP3A4CYP1A1 | |
| SCHEMBL29628977 | 0.80 | CYP3A4 (0.77) | ACHEDYRK1ACLK4CYP3A4CYP1A1 | |
| Ammonia Solution, Strong SCHEMBL27960505 | 0.80 | CYP3A4 (0.70) | ACHEDYRK1ACLK4CYP3A4CYP1A1 | |
| SCHEMBL10013792 | 0.79 | ALOX5 (0.52) | CLK4CYP3A4CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL12565770 | 0.79 | HTR7 (0.53) | ACHECYP3A4CYP1A2CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492274-B1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE AND USE THEREOF | UNIV ZHEJIANG (CN) | 2016-09-21 | — | — | EP | disclosed |
| EP-2492274-B1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE AND USE THEREOF | UNIV ZHEJIANG (CN) | 2016-09-21 | — | — | EP | disclosed |
| US-9006491-B2 | Structure and method for synthesizing and using dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate | ZHEJIANG UNIVERSITY (CN) | 2015-04-14 | — | — | US | disclosed |
| US-9006491-B2 | Structure and method for synthesizing and using dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate | ZHEJIANG UNIVERSITY (CN) | 2015-04-14 | — | — | US | disclosed |
| US-9006491-B2 | Structure and method for synthesizing and using dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate | ZHEJIANG UNIVERSITY (CN) | 2015-04-14 | — | — | US | disclosed |
| EP-2492274-A1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE, PREPARATION METHOD AND USE THEREOF | Zhejiang University (CN) | 2012-08-29 | — | — | EP | disclosed |
| EP-2492274-A1 | 2,4,6- OR 2,6-ALKOXYPHENYL DIALKYLPHOSPHINE, TETRAFLUOROBORATE, PREPARATION METHOD AND USE THEREOF | Zhejiang University (CN) | 2012-08-29 | — | — | EP | disclosed |
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | ZHEJIANG UNIVERSITY (CN) | 2012-08-02 | — | — | US | disclosed |
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | ZHEJIANG UNIVERSITY (CN) | 2012-08-02 | — | — | US | disclosed |
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | ZHEJIANG UNIVERSITY (CN) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197030-A1 | STRUCTURE AND METHOD FOR SYNTHESIZING AND USING DIALKYL(2,4,6- OR 2,6-ALKOXYPHENYL)PHOSPHINE AND ITS TETRAFLUOROBORATE | PTK6, DCLK2, ERBB2 | ACHE 2414/4885DYRK1A 119/4885CLK4 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.