Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11896715 | 0.92 | CA12 (0.59) | CA12CA1CA2CA9PKM | |
| SCHEMBL13557760 | 0.84 | CA12 (0.65) | CA12CA1CA2CA9PKM | |
| SCHEMBL10025883 | 0.81 | CA12 (0.59) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL31019320 | 0.80 | GBA1 (0.58) | CA12CA1CA2CA9PKM | |
| SCHEMBL19326757 | 0.80 | CA12 (0.69) | CA12CA1CA2CA9PKM | |
| SCHEMBL19326750 | 0.79 | CA12 (0.67) | CA12CA1CA2CA9PKM | |
| SCHEMBL18400069 | 0.79 | CA12 (0.60) | CA12CA1CA2CA9PKM | |
| SCHEMBL26666656 | 0.79 | CA12 (0.56) | CA12CA1CA2CA9PKM | |
| SCHEMBL26666650 | 0.79 | CA12 (0.56) | CA12CA1CA2CA9PKM | |
| SCHEMBL17432063 | 0.78 | PKM (0.56) | CA12CA1CA2CA9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623627-B2 | Labelling of fusion proteins with synthetic probes | NEW ENGLAND BIOLABS, INC (US) | 2014-01-07 | — | — | US | disclosed |
| US-20130130291-A1 | Labelling of Fusion Proteins with Synthetic Probes | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2013-05-23 | — | — | US | disclosed |
| US-20120237961-A1 | Labelling of Fusion Proteins with Synthetic Probes | GAUTIER ARNAUD (CH) | 2012-09-20 | — | — | US | disclosed |
| US-8227602-B2 | Labelling of fusion proteins with synthetic probes | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2012-07-24 | — | — | US | disclosed |
| US-20110207157-A1 | Labelling of Fusion Proteins With Synthetic Probes | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207157-A1 | Labelling of Fusion Proteins With Synthetic Probes | GART, ALKBH2, ATIC | CA12 3858/4885CA1 4372/4885CA2 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.