Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1741180 | 1.00 | SPHK1 (0.38) | SPHK1PTPN1GPR84FFAR1FAAH | |
| SCHEMBL1741163 | 0.98 | SPHK1 (0.35) | SPHK1PTPN1GPR84FFAR1FAAH | |
| SCHEMBL1742940 | 0.86 | CA2 (0.30) | CA2 | |
| SCHEMBL10926505 | 0.81 | GPR84 (0.36) | SPHK1PTPN1GPR84FFAR1FAAH | |
| SCHEMBL1114632 | 0.81 | PTPN1 (0.40) | SPHK1PTPN1LMNACA2 | |
| SCHEMBL9033731 | 0.81 | ACE2 (0.41) | GPR84FFAR1FAAHCA2 | |
| SCHEMBL1114641 | 0.81 | PTPN1 (0.40) | SPHK1PTPN1LMNACA2 | |
| SCHEMBL29910754 | 0.81 | GPR84 (0.37) | SPHK1GPR84FFAR1LMNACA2 | |
| SCHEMBL9117823 | 0.81 | GPR84 (0.37) | SPHK1GPR84FFAR1LMNACA2 | |
| SCHEMBL11898965 | 0.80 | SPHK1 (0.46) | SPHK1PTPN1GPR84FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202287-A1 | Stem Cell Culture Methods | ITI SCOTLAND LIMITED (GB) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202287-A1 | Stem Cell Culture Methods | KIT, SOX18, MCL1 | SPHK1 3188/4885PTPN1 3340/4885GPR84 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.