SCHEMBL119010

SCHEMBL119010

O=C(O)CN(CC(=O)O)C[C@H](Cc1ccc(NC(=S)NCCO)cc1)N(CC(=O)O)CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.44
KMT2A Q03164 3/20 0.43
GAA P10253 2/20 0.43
CDK1 P06493 1/20 0.41
ALDH1A1 P00352 4/20 0.41
CA2 P00918 4/20 0.39
CA9 Q16790 2/20 0.39
CA1 P00915 3/20 0.38
ABAT P80404 1/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX12 P18054 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13224653 0.83 LMNA (0.45) LMNAKMT2AGAAALDH1A1MAPT
SCHEMBL21554140 0.82 LMNA (0.42) LMNAKMT2AGAAALDH1A1MAPT
SCHEMBL17325863 0.80 ALDH1A1 (0.41) LMNAKMT2AGAAALDH1A1CA2
SCHEMBL438288 0.79 OPRM1 (0.42) LMNAKMT2AALDH1A1CA2CA9
SCHEMBL20079622 0.79 ALDH1A1 (0.41) LMNAKMT2AALDH1A1CA2CA9
SCHEMBL20079589 0.79 ALDH1A1 (0.40) LMNAKMT2AALDH1A1CA2CA1
SCHEMBL2538468 0.79 KMT2A (0.43) KMT2ACA2CA9CA1MEN1
SCHEMBL7170464 0.79 KMT2A (0.43) KMT2ACA2CA9CA1MEN1
SCHEMBL23298428 0.77 CA1 (0.42) CA2CA9CA1CA12
SCHEMBL17922627 0.77 CA1 (0.39) KMT2ACA2CA9CA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5367 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5273743-A A compound made up of three different Fab'-like fragments linked by a bis- or trissuccinimidyl moiety; retention of antigen binding acitivity HYBRITECH INCORPORATED (US) 1993-12-28 US claimed
EP-0453082-A1 Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent HYBRITECH INCORPORATED (US) 1991-10-23 EP claimed
CN-122094980-A Bispecific antibody fusion molecules targeting CD180 and CD3 and methods of use thereof 2026-05-26 CN disclosed
EP-4731677-A2 ENGINEERED BISPECIFIC MOLECULES AND METHODS OF USE Cantai Therapeutics Inc. (US) 2026-04-29 EP disclosed
US-12583922-B2 Bispecific antibodies targeting CD47 and PD-L1 and methods of use thereof NOVIMMUNE SA (CH) 2026-03-24 US disclosed
US-20260078425-A1 METHODS OF PROTEIN PRODUCTION GENENTECH, INC. (US) 2026-03-19 US disclosed
EP-4706769-A2 ANTI-CD47 ANTIBODIES AND METHODS OF USE THEREOF NovImmune SA (CH) 2026-03-11 EP disclosed
US-20260061068-A1 COMPOSITIONS AND METHODS RELATED TO ANTI-CD19 ANTIBODY DRUG CONJUGATES LIGACHEM BIOSCIENCES INC (KR) 2026-03-05 US disclosed
US-12559566-B2 CD37-binding molecules immunoconjugates thereof DEBIOPHARM INTERNATIONAL, S.A. (CH) 2026-02-24 US disclosed
US-20260049135-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES GENENTECH INC (US) 2026-02-19 US disclosed
US-12534465-B2 5H-pyrrolo[3,2-d]pyrimidine-2,4-diamino compounds and antibody conjugates thereof SUTRO BIOPHARMA, INC. (US) 2026-01-27 US disclosed
US-5112951-A Elution from sulfonated solid support HYBRITECH INCORPORATED (US) 1992-05-12 US disclosed
US-5091542-A Trivalent coupling agents for linking fab fragments to form bifunctional and trifunctional antibody-like compounds HYBRITECH INCORPORATED (US) 1992-02-25 US disclosed
EP-0453082-A1 Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent HYBRITECH INCORPORATED (US) 1991-10-23 EP disclosed
EP-0446071-A2 Tris-maleimido compounds as intermediates in trifunctional antibody synthesis HYBRITECH INCORPORATED (US) 1991-09-11 EP disclosed
EP-0415557-A2 Separation of anti-metal chelate antibodies HYBRITECH INCORPORATED (US) 1991-03-06 EP disclosed
EP-0369566-A2 Bifunctional chimeric antibodies HYBRITECH INCORPORATED (US) 1990-05-23 EP disclosed
EP-0369567-A2 Chimeric antibodies directed against metal chelates HYBRITECH INCORPORATED (US) 1990-05-23 EP disclosed
EP-0327365-A2 Improvements in or relating to modified haptens useful as imaging and therapeutic agents HYBRITECH INCORPORATED (US) 1989-08-09 EP disclosed
EP-0315456-A2 Polysaccharide-modified immunoglobulins having reduced immunogenic potential or improved pharmacokinetics HYBRITECH INCORPORATED (US) 1989-05-10 EP disclosed