Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653865 | 0.80 | SMN1; SMN2 (0.47) | TSHRALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL118131 | 0.72 | SMN1; SMN2 (0.49) | TSHRALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL11903314 | 0.71 | HSD17B10 (0.35) | TSHRALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL1653862 | 0.71 | HSD17B10 (0.34) | TSHRALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL1656981 | 0.68 | TSHR (0.52) | TSHRALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL719555 | 0.67 | NPSR1 (0.48) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPT | |
| SCHEMBL29352298 | 0.67 | NPSR1 (0.48) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPT | |
| SCHEMBL11918046 | 0.66 | TSHR (0.42) | TSHRALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10255541 | 0.66 | NPSR1 (0.47) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3792082 | 0.66 | NPSR1 (0.47) | ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | TSHR 2970/4885ALDH1A1 718/4885HPGD 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.