Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653862 | 0.72 | HSD17B10 (0.34) | HSD17B10LMNAMAPTCFTRKDM4E | |
| SCHEMBL1653865 | 0.71 | SMN1; SMN2 (0.47) | HSD17B10LMNAMAPTKDM4ETSHR | |
| SCHEMBL11903315 | 0.71 | TSHR (0.39) | HSD17B10LMNAMAPTKDM4ETSHR | |
| SCHEMBL719555 | 0.68 | NPSR1 (0.48) | HSD17B10MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL29352298 | 0.68 | NPSR1 (0.48) | HSD17B10MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL10255541 | 0.66 | NPSR1 (0.47) | KDM4EALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL12338199 | 0.66 | NPSR1 (0.47) | HSD17B10LMNAMAPTKDM4EKMT2A | |
| SCHEMBL3792082 | 0.66 | NPSR1 (0.47) | KDM4EALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL719803 | 0.65 | NPSR1 (0.45) | HSD17B10KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL30959691 | 0.65 | PIN1 (0.46) | HSD17B10LMNAMAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | HSD17B10 171/4885LMNA 4587/4885MAPT 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.