Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903008 | 0.83 | TSHR (0.43) | TSHRALDH1A1LMNAMAPTGAA | |
| SCHEMBL11902918 | 0.81 | TSHR (0.42) | TSHRALDH1A1LMNAMAPTGAA | |
| SCHEMBL11902325 | 0.71 | ALDH1A1 (0.40) | TSHRALDH1A1LMNAMAPTGAA | |
| SCHEMBL11918046 | 0.69 | TSHR (0.42) | TSHRALDH1A1LMNAMAPTGAA | |
| SCHEMBL118131 | 0.69 | SMN1; SMN2 (0.49) | TSHRALDH1A1LMNAMAPTPOLB | |
| SCHEMBL20119920 | 0.69 | KMT2A (0.48) | ALDH1A1LMNAMAPTPOLBHTT | |
| SCHEMBL1653865 | 0.68 | SMN1; SMN2 (0.47) | TSHRALDH1A1LMNAMAPTGAA | |
| SCHEMBL11903315 | 0.68 | TSHR (0.39) | TSHRALDH1A1LMNAMAPTGAA | |
| SCHEMBL11903049 | 0.66 | GAA (0.41) | TSHRALDH1A1LMNAMAPTGAA | |
| SCHEMBL11903164 | 0.66 | CCR2 (0.38) | TSHRALDH1A1MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488518-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| CN-102574849-A | Herbicidal compounds | SYNGENTA LTD | 2012-07-11 | — | — | CN | disclosed |
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | TSHR 2970/4885ALDH1A1 718/4885LMNA 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.