Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27830114 | 0.79 | POLB (0.47) | POLBESR1ESR2KMT2AUSP2 | |
| SCHEMBL6662281 | 0.76 | PIM1 (0.46) | TDP1KCNH2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL27814695 | 0.75 | KMT2A (0.49) | POLBESR1ESR2KMT2AUSP2 | |
| SCHEMBL27753293 | 0.72 | NNMT (0.53) | PKMPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL20815627 | 0.72 | L3MBTL1 (0.47) | POLBESR1ESR2KMT2AHTT | |
| SCHEMBL29447025 | 0.71 | NNMT (0.56) | POLBKMT2ATDP1KCNH2MEN1 | |
| SCHEMBL2304053 | 0.71 | NNMT (0.56) | POLBKMT2ATDP1KCNH2MEN1 | |
| SCHEMBL21410586 | 0.70 | KMT2A (0.46) | PKMPOLBESR1ESR2KMT2A | |
| SCHEMBL24500157 | 0.69 | KMT2A (0.68) | POLBKMT2AUSP2HTTSMN1; SMN2 | |
| SCHEMBL2406824 | 0.69 | ESR1 (0.61) | POLBESR1ESR2KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370773-B | Cycloalkanecarboxamide derivative and method for producing same | SEIKAGAKU KOGYO CO LTD | 2014-04-09 | — | — | CN | disclosed |
| EP-1975162-B1 | OXAZOLONE DERIVATIVE | SEIKAGAKU KOGYO CO LTD (JP) | 2012-08-15 | — | — | EP | disclosed |
| CN-101370773-A | Cycloalkanecarboxamide derivative and method for producing same | SEIKAGAKU KOGYO CO LTD (JP) | 2009-02-18 | — | — | CN | disclosed |