SCHEMBL27753293

SCHEMBL27753293

NC(=O)c1ccc(OC(=O)C2CCCCC2)nc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 1/20 0.46
ELANE P08246 1/20 0.46
RAB9A P51151 2/20 0.44
ATM Q13315 1/20 0.44
PARP15 Q460N3 2/20 0.43
PARP10 Q53GL7 2/20 0.43
HRH3 Q9Y5N1 1/20 0.43
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
OPRK1 P41145 1/20 0.42
KCNH2 Q12809 1/20 0.42
NPC1 O15118 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
MKNK1 Q9BUB5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28590074 0.78 L3MBTL1 (0.50) SMN1; SMN2POLBELANERAB9AHTT
SCHEMBL24500158 0.77 KMT2A (0.68) SMN1; SMN2POLBELANERAB9AATM
SCHEMBL24500157 0.77 KMT2A (0.68) SMN1; SMN2POLBELANERAB9AATM
SCHEMBL17570206 0.76 ELANE (0.54) SMN1; SMN2POLBELANERAB9AATM
SCHEMBL19185924 0.75 KMT2A (0.51) SMN1; SMN2POLBELANERAB9AATM
SCHEMBL28422556 0.75 SMN1; SMN2 (0.50) SMN1; SMN2POLBELANERAB9AATM
SCHEMBL8343389 0.73 MAPT (0.47) POLBELANE
SCHEMBL21628532 0.73 OPRM1 (0.54) NNMTPARP15PARP10HRH3OPRK1
SCHEMBL21628507 0.73 OPRM1 (0.54) NNMTPARP15PARP10HRH3OPRK1
SCHEMBL11904090 0.72 PKM (0.48) SMN1; SMN2POLBELANERAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101370773-B Cycloalkanecarboxamide derivative and method for producing same SEIKAGAKU KOGYO CO LTD 2014-04-09 CN disclosed
CN-101370773-A Cycloalkanecarboxamide derivative and method for producing same SEIKAGAKU KOGYO CO LTD (JP) 2009-02-18 CN disclosed