Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SDCBP | O00560 | 1/20 | 0.47 |
| ▸ | SDC2 | P34741 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668757 | 0.93 | NR1H4 (0.59) | ALDH1A1L3MBTL1HDAC1LMNAEPHX2 | |
| SCHEMBL1668726 | 0.88 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL31606699 | 0.87 | CA1 (0.54) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL595225 | 0.86 | CA12 (0.52) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL3608658 | 0.86 | EPHX2 (0.62) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL10227120 | 0.86 | FAAH (0.64) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL23462113 | 0.85 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL23884201 | 0.85 | HDAC1 (0.56) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL1852791 | 0.83 | EPHX2 (0.58) | L3MBTL1CA12CA1CA2HDAC1 | |
| SCHEMBL19553789 | 0.83 | EPHX2 (0.51) | ALDH1A1L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |