Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015321 | 1.00 | ALOX5 (0.43) | ALOX5NOD2NOD1HRH3THRB | |
| SCHEMBL11904992 | 1.00 | ALOX5 (0.43) | ALOX5NOD2NOD1HRH3THRB | |
| SCHEMBL10003966 | 0.94 | HTR6 (0.39) | ALOX5NOD2NOD1THRBCYP3A4 | |
| SCHEMBL10003964 | 0.94 | HTR6 (0.39) | ALOX5NOD2NOD1THRBCYP3A4 | |
| SCHEMBL11931229 | 0.94 | HTR6 (0.39) | ALOX5NOD2NOD1THRBCYP3A4 | |
| SCHEMBL18332262 | 0.86 | NOD2 (0.41) | ALOX5NOD2NOD1ALDH1A1NPSR1 | |
| SCHEMBL10003580 | 0.83 | ALOX5 (0.39) | ALOX5NOD2NOD1ALDH1A1NPSR1 | |
| SCHEMBL10003582 | 0.83 | ALOX5 (0.39) | ALOX5NOD2NOD1ALDH1A1NPSR1 | |
| SCHEMBL10003677 | 0.83 | SLC2A1 (0.36) | ALOX5ALDH1A1NPSR1HTTLMNA | |
| SCHEMBL10003675 | 0.83 | SLC2A1 (0.36) | ALOX5ALDH1A1NPSR1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471786-B1 | AMINOPYRAZOLE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-8829199-B2 | Aminopyrazole derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20120208811-A1 | Aminopyrazole Derivative | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208811-A1 | Aminopyrazole Derivative | FGFR1, FGFR3, FGFR4 | ALOX5 2600/4885NOD2 2641/4885NOD1 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.