Sugi Predict

Sugi Predict / Compounds / Arginine

Arginine

Arginine

SCHEMBL11905093

CC[C@H](C)[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 3/20 0.38
▸ NOS2 P35228 3/20 0.34
▸ NOS3 P29474 2/20 0.34
▸ NOS1 P29475 2/20 0.34
▸ DPP7 Q9UHL4 1/20 0.33
▸ OTC P00480 1/20 0.33
▸ DDAH1 O94760 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ MAPK8 P45983 1/20 0.31
▸ MAPK9 P45984 1/20 0.31
▸ MAPK10 P53779 1/20 0.31
▸ TLR2 O60603 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL23248653 1.00 PRCP (0.38) PRCPNOS2NOS3NOS1DPP7
Arginine SCHEMBL14841994 1.00 PRCP (0.38) PRCPNOS2NOS3NOS1DPP7
Arginine SCHEMBL25168271 0.97 PRCP (0.36) PRCPNOS2NOS3NOS1DPP7
Arginine SCHEMBL11905292 0.97 PRCP (0.35) PRCPNOS2NOS3NOS1DPP7
Arginine SCHEMBL17982370 0.96 PRCP (0.36) PRCPNOS2NOS3NOS1DPP7
Arginine SCHEMBL2501111 0.96 PRCP (0.36) PRCPNOS2NOS3NOS1DPP7
Arginine SCHEMBL1551248 0.95 PRCP (0.35) PRCPNOS2NOS3NOS1DPP7
Arginine SCHEMBL25171512 0.92 PRCP (0.33) PRCP
Arginine SCHEMBL4223569 0.92 PRCP (0.33) PRCPKMT2AMAPK8MAPK9MAPK10
Arginine SCHEMBL28465970 0.91 PRCP (0.33) PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111329779-B Active peptide composition for promoting hair growth and application thereof 烟台中科恩吉科创新产业园管理有限公司 2022-09-13 — — CN claimed
CN-111329779-A Active peptide composition for promoting hair growth and application thereof 烟台中科恩吉科创新产业园管理有限公司 2020-06-26 — — CN claimed
US-9091700-B2 Modified peptide substrate MCMASTER UNIVERSITY (CA) 2015-07-28 — — US claimed
US-20120208225-A1 MODIFIED PEPTIDE SUBSTRATE THE UNIVERSITY OF MELBOURNE (AU) 2012-08-16 — — US claimed
CN-111329779-B Active peptide composition for promoting hair growth and application thereof 烟台中科恩吉科创新产业园管理有限公司 2022-09-13 — — CN disclosed
CN-111329779-B Active peptide composition for promoting hair growth and application thereof 烟台中科恩吉科创新产业园管理有限公司 2022-09-13 — — CN disclosed
CN-111329779-A Active peptide composition for promoting hair growth and application thereof 烟台中科恩吉科创新产业园管理有限公司 2020-06-26 — — CN disclosed
CN-111329779-A Active peptide composition for promoting hair growth and application thereof 烟台中科恩吉科创新产业园管理有限公司 2020-06-26 — — CN disclosed
US-10131932-B2 Method for assaying a protease MCMASTER UNIVERSITY 2018-11-20 — — US disclosed
EP-3047033-B1 METHOD FOR ASSAYING A PROTEASE UNIV MCMASTER (CA) 2018-08-22 — — EP disclosed
US-20160326569-A1 METHOD FOR ASSAYING A PROTEASE MCMASTER UNIVERSITY (CA) 2016-11-10 — — US disclosed
EP-3047033-A1 METHOD FOR ASSAYING A PROTEASE Mcmaster University (CA) 2016-07-27 — — EP disclosed
US-9091700-B2 Modified peptide substrate MCMASTER UNIVERSITY (CA) 2015-07-28 — — US disclosed
WO-2015039211-A1 METHOD FOR ASSAYING A PROTEASE MCMASTER UNIVERSITY (CA) 2015-03-26 — — WO disclosed
US-20120208225-A1 MODIFIED PEPTIDE SUBSTRATE THE UNIVERSITY OF MELBOURNE (AU) 2012-08-16 — — US disclosed