Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL11905093 | 1.00 | PRCP (0.38) | PRCPNOS2NOS3NOS1DPP7 | |
| Arginine SCHEMBL14841994 | 1.00 | PRCP (0.38) | PRCPNOS2NOS3NOS1DPP7 | |
| Arginine SCHEMBL25168271 | 0.97 | PRCP (0.36) | PRCPNOS2NOS3NOS1DPP7 | |
| Arginine SCHEMBL11905292 | 0.97 | PRCP (0.35) | PRCPNOS2NOS3NOS1DPP7 | |
| Arginine SCHEMBL17982370 | 0.96 | PRCP (0.36) | PRCPNOS2NOS3NOS1DPP7 | |
| Arginine SCHEMBL2501111 | 0.96 | PRCP (0.36) | PRCPNOS2NOS3NOS1DPP7 | |
| Arginine SCHEMBL1551248 | 0.95 | PRCP (0.35) | PRCPNOS2NOS3NOS1DPP7 | |
| Arginine SCHEMBL25171512 | 0.92 | PRCP (0.33) | PRCP | |
| Arginine SCHEMBL4223569 | 0.92 | PRCP (0.33) | PRCPKMT2AMAPK8MAPK9MAPK10 | |
| Arginine SCHEMBL28465970 | 0.91 | PRCP (0.33) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677690-B | Peptides for alleviating hair loss and promoting hair growth, cosmetic composition and pharmaceutical composition containing the same | 因科斯医药公司 | 2024-03-12 | — | — | CN | disclosed |
| EP-4047008-A2 | PEPTIDE FOR REDUCING HAIR LOSS AND PROMOTING HAIR GROWTH, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Incospharm Corporation (KR) | 2022-08-24 | — | — | EP | disclosed |
| US-20220160608-A1 | PEPTIDE FOR REDUCING HAIR LOSS AND PROMOTING HAIR GROWTH, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | INCOSPHARM CORPORATION (KR) | 2022-05-26 | — | — | US | disclosed |
| CN-113677690-A | Peptide for alleviating hair loss and promoting hair growth, cosmetic composition and pharmaceutical composition comprising the same | 因科斯医药公司 | 2021-11-19 | — | — | CN | disclosed |
| WO-2021075791-A2 | PEPTIDE FOR REDUCING HAIR LOSS AND PROMOTING HAIR GROWTH, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 인코스팜 | 2021-04-22 | — | — | WO | disclosed |
| WO-2021075792-A1 | PEPTIDE COMPOSITION FOR IMPROVING SCALP HEALTH AND ALLEVIATING HAIR LOSS | 주식회사 인코스팜 | 2021-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160608-A1 | PEPTIDE FOR REDUCING HAIR LOSS AND PROMOTING HAIR GROWTH, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | MMP7, MMP13, MMP9 | PRCP 184/4885NOS2 1333/4885NOS3 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.