Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL11907447 | 0.90 | TSHR (0.43) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL26444 | 0.89 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL503312 | 0.89 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL437181 | 0.89 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL26443 | 0.89 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| Water SCHEMBL4754408 | 0.87 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL2724117 | 0.87 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL22285084 | 0.87 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Water SCHEMBL4754409 | 0.87 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Water SCHEMBL8721103 | 0.87 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689330-B2 | Amino acid derivatives and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-20200165192-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2020-05-28 | — | — | US | disclosed |
| US-10550072-B2 | Amino acid derivatives and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180194717-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2018-07-12 | — | — | US | disclosed |
| EP-2673259-B1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2018-04-11 | — | — | EP | disclosed |
| US-9868696-B2 | Amino acid derivatives and absorbable polymers therefrom | Bezwada Biomedial, LLC (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160257643-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2016-09-08 | — | — | US | disclosed |
| US-20150174290-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2015-06-25 | — | — | US | disclosed |
| US-9012677-B2 | Amino acid derivatives and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-20150065586-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2015-03-05 | — | — | US | disclosed |
| US-8901341-B2 | Amino acid derivatives and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| EP-2673259-A2 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | Bezwada Biomedical, LLC (US) | 2013-12-18 | — | — | EP | disclosed |
| US-20130245133-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-8461372-B2 | Amino acid derivatives and absorbable polymers therefrom | BEZWADA BIOMEDICAL, LLC | 2013-06-11 | — | — | US | disclosed |
| WO-2012109535-A2 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2012-08-16 | — | — | WO | disclosed |
| US-20120208896-A1 | AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC. (US) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208896-A1 | AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM | SLC7A1, SLC3A2, BCAT2 | SLC7A5 19/4885ALPI 676/4885PKM 87/4885 |
| US-20150065586-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
| US-20130245133-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
| US-20160257643-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
| US-10550072-B2 | Amino acid derivatives and absorbable polymers therefrom | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
| US-10689330-B2 | Amino acid derivatives and absorbable polymers therefrom | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
| US-20150174290-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
| US-20180194717-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
| US-20200165192-A1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | SRRM2, SLC7A1, BCAT2 | SLC7A5 28/4885ALPI 1492/4885PKM 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.