SCHEMBL1190763

SCHEMBL1190763

O=C1C=CC(=O)N1c1ccc(Br)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 1.00
FAAH O00519 6/20 1.00
HSP90AA1 P07900 3/20 0.60
TDP1 Q9NUW8 2/20 0.60
PKM P14618 1/20 0.60
MAPK1 P28482 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
BCHE P06276 1/20 0.54
DDAH1 O94760 1/20 0.54
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
CCR6 P51684 1/20 0.52
CACNA1B Q00975 1/20 0.52
APBA1 Q02410 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824448 0.88 MGLL (0.77) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL95324 0.87 MGLL (1.00) MGLLFAAHHSP90AA1TDP1PKM
Methacrylic Acid SCHEMBL5971980 0.82 MGLL (0.67) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL7059051 0.80 MGLL (0.71) MGLLFAAHHSP90AA1
SCHEMBL19511560 0.79 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL21630074 0.79 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL1321309 0.79 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL9839165 0.77 MGLL (0.79) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL19707275 0.75 FAAH (0.60) MGLLFAAHHSP90AA1MAPK1NPSR1
SCHEMBL140025 0.75 MGLL (1.00) MGLLFAAHHSP90AA1TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114843403-B Method for regulating and controlling doping characteristics of two-dimensional material through click chemistry reaction and application 浙江大学 2025-04-04 CN claimed
CN-115948751-B Method for electrocatalytic ring-opening dihydro-alkoxylation reaction of N-aryl maleimide and alcohol 广西师范大学 2024-10-01 CN claimed
CN-117024659-B Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2024-05-31 CN claimed
WO-2023216852-A1 METHOD FOR REGULATING DOPING CHARACTERISTICS OF TWO-DIMENSIONAL MATERIAL BY CLICK CHEMICAL REACTION, AND APPLICATION 浙江大学 2023-11-16 WO claimed
CN-117024659-A Preparation method of large-particle-size high-solid-content styrene-butadiene latex 河南大树实业有限公司 2023-11-10 CN claimed
CN-115591418-B Diaphragm for trapping dioxin and preparation method thereof 佛山(华南)新材料研究院 2023-06-09 CN claimed
CN-113546683-B Application of covalent organic framework material based on porphyrin in photocatalytic oxidation cyclization reaction 山东师范大学 2023-04-28 CN claimed
CN-115591418-A Membrane for trapping dioxin and preparation method thereof 佛山(华南)新材料研究院(CN) 2023-01-13 CN claimed
CN-114843403-A Method for regulating and controlling two-dimensional material doping characteristics through click chemical reaction and application 浙江大学 2022-08-02 CN claimed
CN-113546683-A Application of covalent organic framework material based on porphyrin in photocatalytic oxidation cyclization reaction 山东师范大学 2021-10-26 CN claimed
US-4764558-A Alkyl vinyl ether/N-arylmaleimide copolymer containing polymer alloy ARCO CHEMICAL COMPANY (US) 1988-08-16 US claimed
EP-0253624-A2 Acrylic modified N-arylmaleimide copolymer molding composition ARCO CHEMICAL TECHNOLOGY, INC. (US) 1988-01-20 EP claimed
EP-0247257-A1 Polymer composition containing polycarbonate, a styrenic/maleimide/cyclic anhydride terpolymer and a terpolymer grafted to a polymer matrix ARCO Chemical Technology, L.P. (US) 1987-12-02 EP claimed
US-4701493-A EMULSION POLYMERIZATION ATLANTIC RICHFIELD COMPANY (US) 1987-10-20 US claimed
EP-0220909-A2 Thermodynamically miscible polymer composition ARCO Chemical Technology, L.P. (US) 1987-05-06 EP claimed
EP-0196872-A2 Molding composition containing functionalised thermoplastic rubber and method ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-10-08 EP claimed
EP-0194384-A1 Thermodynamically miscible polymer compostions ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-09-17 EP claimed
US-4605700-A OLEFIN-MALEIMIDE COPOLYMER AND ACRYLONITRILE-VINYL AROMATIC COPOLYMER BLEND HAVING A SINGLE GLASS TRANSITION TEMPERATURE; MOLDINGS ATLANTIC RICHFIELD COMPANY (US) 1986-08-12 US claimed
US-4588774-A MOLDING MATERIALS, MALEIMIDE MONOMER, GRAFTED SYNTHETIC RUBBERS ATLANTIC RICHFIELD COMPANY (US) 1986-05-13 US claimed
US-4497928-A Moldable polyblend containing poly(arylene sulfide) ATLANTIC RICHFIELD COMPANY (US) 1985-02-05 US claimed