Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473669 | 0.91 | PTPN11 (0.39) | CYP11B1CYP11B2PTGDR2SMN1; SMN2CYP2C9 | |
| SCHEMBL1560920 | 0.87 | CYP11B1 (0.38) | CYP11B1CYP11B2SMN1; SMN2CKS1BSKP2 | |
| SCHEMBL11929456 | 0.85 | SLC2A1 (0.44) | SLC2A1CYP11B1CYP11B2CYP19A1NR4A2 | |
| SCHEMBL1560999 | 0.84 | ABCB1 (0.37) | CYP11B1CYP11B2PTGDR2ABCB1SMN1; SMN2 | |
| SCHEMBL1561368 | 0.84 | POLB (0.36) | CYP11B1CYP11B2PTGDR2ABCB1SMN1; SMN2 | |
| SCHEMBL2218828 | 0.83 | PIM1 (0.41) | CYP11B1CYP11B2PTGDR2SMN1; SMN2CYP2C9 | |
| SCHEMBL1559921 | 0.83 | ABCB1 (0.41) | CYP11B1CYP11B2ABCB1CKS1BSKP2 | |
| SCHEMBL1560996 | 0.82 | CTPS1 (0.40) | CYP11B1CYP11B2CKS1BSKP2 | |
| SCHEMBL2220367 | 0.82 | CYP2A6 (0.40) | CYP11B1CYP11B2PTGDR2SMN1; SMN2CYP2C9 | |
| SCHEMBL473708 | 0.82 | CYP2A6 (0.40) | CYP11B1CYP11B2PTGDR2SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208809-A1 | 9H-PYRROLO[2,3-B: 5,4-C'] DIPYRIDINE AZACARBOLINE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208809-A1 | 9H-PYRROLO[2,3-B: 5,4-C'] DIPYRIDINE AZACARBOLINE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | NPR3, CCNH, CBR3 | SLC2A1 4284/4885CYP11B1 422/4885CYP11B2 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.