Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2218828 | 0.91 | PIM1 (0.41) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL473708 | 0.89 | CYP2A6 (0.40) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL2218482 | 0.87 | CYP2A6 (0.38) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL1560920 | 0.86 | CYP11B1 (0.38) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL473783 | 0.84 | CYP2A6 (0.42) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL473669 | 0.84 | PTPN11 (0.39) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL1561368 | 0.83 | POLB (0.36) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL11908027 | 0.82 | SLC2A1 (0.41) | CYP2A6CYP11B1CYP11B2SMN1; SMN2CKS1B | |
| SCHEMBL12435456 | 0.81 | CYP2A6 (0.43) | CYP2A6CYP11B1CYP11B2PIM1CYP3A4 | |
| SCHEMBL1560999 | 0.81 | ABCB1 (0.37) | CYP2A6CYP11B1CYP11B2PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | AOC3, CBR3, IDH3B | CYP2A6 705/4885CYP11B1 332/4885CYP11B2 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.