SCHEMBL11908029

SCHEMBL11908029

O=C(OC1C2CC3CC(C2)CC1C3)C1CC2C=CC1C2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
KDM4E B2RXH2 1/20 0.45
EPHX2 P34913 3/20 0.43
HSD11B1 P28845 1/20 0.38
ALDH1A1 P00352 7/20 0.38
KMT2A Q03164 2/20 0.37
RAB9A P51151 1/20 0.37
EPHX1 P07099 1/20 0.36
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
ESR2 Q92731 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 1/20 0.36
FKBP1A P62942 1/20 0.34
ESR1 P03372 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11907615 0.84 ALDH1A1 (0.47) LMNAKDM4EEPHX2HSD11B1ALDH1A1
SCHEMBL11909408 0.81 ALDH1A1 (0.41) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL22263806 0.79 ALDH1A1 (0.46) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL3870190 0.77 ATM (0.43) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL13382568 0.76 LMNA (0.50) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL16534212 0.76 KDM4E (0.38) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL2201028 0.75 LMNA (0.57) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL14378676 0.75 LMNA (0.57) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL2776167 0.75 LMNA (0.57) LMNAKDM4EEPHX2ALDH1A1KMT2A
SCHEMBL14602097 0.75 LMNA (0.37) LMNAKDM4EALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3824054-A2 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES Promerus, LLC (US) 2021-05-26 EP disclosed
WO-2020018485-A2 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES PROMERUS, LLC (US) 2020-01-23 WO disclosed
WO-2020018485-A2 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES PROMERUS, LLC (US) 2020-01-23 WO disclosed
US-9394333-B2 Method for the synthesis of phosphorus atom modified nucleic acids WAVE LIFE SCIENCES JAPAN (JP) 2016-07-19 US disclosed
US-8450440-B2 Method for purifying polymer and polymer MITSUI CHEMICALS, INC. (JP) 2013-05-28 US disclosed
US-20120208976-A1 METHOD FOR PURIFYING POLYMER AND POLYMER MITSUI CHEMICALS, INC (JP) 2012-08-16 US disclosed