SCHEMBL3870190

SCHEMBL3870190

O=C(OC1CC2CCC1C2)C1CC2C=CC1C2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CYP19A1 P11511 1/20 0.40
ALDH1A1 P00352 5/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
GRM1 Q13255 3/20 0.35
KMT2A Q03164 2/20 0.35
RAB9A P51151 1/20 0.35
EPHX2 P34913 1/20 0.35
POLB P06746 2/20 0.34
APEX1 P27695 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
ESR2 Q92731 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HPGD P15428 1/20 0.34
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11907466 0.86 ALDH1A1 (0.45) ATMKDM4ELMNACYP19A1ALDH1A1
SCHEMBL22263738 0.85 ALDH1A1 (0.39) ATMKDM4ELMNACYP19A1ALDH1A1
SCHEMBL1088861 0.82 ALDH1A1 (0.38) ATMKDM4ELMNACYP19A1ALDH1A1
SCHEMBL12481918 0.81 KDM4E (0.42) KDM4ELMNAALDH1A1TDP1GAA
SCHEMBL13382568 0.79 LMNA (0.50) KDM4ELMNAALDH1A1TDP1KMT2A
SCHEMBL12228753 0.77 ATM (0.53) ATMKDM4ECYP19A1GAAGRM1
SCHEMBL11908029 0.77 LMNA (0.45) KDM4ELMNAALDH1A1TDP1KMT2A
SCHEMBL7609159 0.76 ALDH1A1 (0.40) KDM4ELMNAALDH1A1TDP1GAA
SCHEMBL13841335 0.76 ALDH1A1 (0.41) KDM4ELMNAALDH1A1TDP1GAA
SCHEMBL3870095 0.75 KDM4E (0.41) KDM4ELMNAALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200115400-A1 METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-04-16 US disclosed
US-8043788-B2 Alkali soluble resin; immersion lithography SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-10-25 US disclosed
US-7598016-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-10-06 US disclosed
US-20090148790-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2009-06-11 US disclosed
US-7521169-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2009-04-21 US disclosed
US-7514204-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-04-07 US disclosed
US-20090011365-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-01-08 US disclosed
US-20080241736-A1 Immersion lithography; copolymer containing ammonium salt of carboxylic acid and fluorine monomer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-10-02 US disclosed
US-20080096131-A1 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-04-24 US disclosed
US-20060234153-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-19 US disclosed
EP-1557718-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200115400-A1 METHOD FOR PRODUCING SILICON COMPOUND, AND SILICON COMPOUND SI, SIK1, CA1 ATM 1308/4885KDM4E 3666/4885LMNA 3637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.