SCHEMBL11908591

SCHEMBL11908591

O=C1CC(=O)N(c2ccco2)C(=O)N1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 14/20 0.54
KMT2A Q03164 14/20 0.54
MAPT P10636 13/20 0.54
HSD17B10 Q99714 5/20 0.54
POLB P06746 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
APEX1 P27695 2/20 0.54
RECQL P46063 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
HBB P68871 2/20 0.54
PSMD14 O00487 1/20 0.54
MMP2 P08253 1/20 0.54
DNMT1 P26358 1/20 0.54
PTPN7 P35236 1/20 0.54
KDM4C Q9H3R0 1/20 0.54
LMNA P02545 1/20 0.49
ALOX12 P18054 3/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
THRB P10828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10764104 0.73 KMT2A (0.34) MEN1KMT2AMAPTHSD17B10POLB
SCHEMBL125016 0.72 MEN1 (0.68) MEN1KMT2AMAPTHSD17B10POLB
SCHEMBL30998809 0.70 MEN1 (0.56) MEN1KMT2AMAPTHSD17B10POLB
SCHEMBL2115613 0.70 MAPT (1.00) MEN1KMT2AMAPTHSD17B10POLB
SCHEMBL15021488 0.69 TLR9 (0.44) TDP1
SCHEMBL11789855 0.68 KMT2A (0.37) MEN1KMT2AMAPTHSD17B10POLB
SCHEMBL11154155 0.68 KMT2A (0.40) MEN1KMT2AMAPTHSD17B10POLB
SCHEMBL6238897 0.67 MAPT (1.00) MEN1KMT2AMAPTHSD17B10L3MBTL1
SCHEMBL11908454 0.67 MEN1 (0.53) MEN1KMT2AMAPTHSD17B10POLB
SCHEMBL10429462 0.67 MAPT (0.67) MEN1KMT2AMAPTHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140212792-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-07-31 US disclosed
US-8728685-B2 Method of making holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-20 US disclosed
EP-2676170-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC Innovative Plastics IP B.V. (NL) 2013-12-25 EP disclosed
WO-2012138421-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-10-11 WO disclosed
US-20120208110-A1 HOLOGRAPHIC STORAGE MEDIUM AND METHOD OF MAKING HOLOGRAPHIC STORAGE MEDIUM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-08-16 US disclosed