Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.56 |
| ▸ | MAPT | P10636 | 13/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HBB | P68871 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125016 | 0.74 | MEN1 (0.68) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL20020500 | 0.71 | MEN1 (0.69) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL125195 | 0.71 | MAPT (1.00) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL8441345 | 0.71 | MEN1 (1.00) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL11908591 | 0.70 | MEN1 (0.54) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL6799176 | 0.69 | MAPT (0.68) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL16322940 | 0.68 | MEN1 (0.55) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL7703374 | 0.68 | MAPT (1.00) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL7701199 | 0.68 | MEN1 (1.00) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL145274 | 0.68 | MEN1 (0.68) | MEN1KMT2AMAPTRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373777-A | Pyrimidine diketone derivative and preparation method and application thereof | 河北科技大学 | 2024-07-23 | — | — | CN | disclosed |