Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29155026 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GAATSHRCTSDSMN1; SMN2 | |
| SCHEMBL31681433 | 0.83 | GLA (0.57) | ALDH1A1TSHRCTSDGLACYP2C9 | |
| SCHEMBL417378 | 0.83 | ALDH1A1 (0.73) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA | |
| SCHEMBL12260755 | 0.82 | CRHBP (0.62) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL27602570 | 0.82 | TSHR (0.68) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL7859174 | 0.81 | TSHR (0.53) | ALDH1A1TSHRCTSDGLACYP2C9 | |
| SCHEMBL2508349 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL960443 | 0.81 | TSHR (0.53) | ALDH1A1TSHRCTSDGLACYP2C9 | |
| SCHEMBL13070932 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL430054 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591192-B | Preparation method of N-cyclopropylmethyl aniline compound | 江西仰立新材料有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-114591192-A | Preparation method of N-cyclopropylmethylaniline compound | 江西仰立新材料有限公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-08-16 | — | — | US | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | SLC6A2 4600/4885SLC6A4 3348/4885SLC6A3 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.