Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.67 |
| ▸ | PAM | P19021 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL3487953 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Methylene Chloride SCHEMBL3349968 | 0.98 | DGKA (0.64) | DGKAPAMTSHRMAPTCYP1A2 | |
| Methylene Chloride SCHEMBL6898274 | 0.98 | DGKA (0.64) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL8375548 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| Hexane SCHEMBL3151787 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL116995 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL454 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| Hexane SCHEMBL2349171 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL6443707 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL1645398 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464942-B2 | Process for the manufacture of ixabepilone | PHARMAREN, LLC (US) | 2019-11-05 | — | — | US | claimed |
| US-20180072749-A1 | PROCESS FOR THE MANUFACTURE OF IXABEPILONE | PHARMAREN, LLC | 2018-03-15 | — | — | US | claimed |
| WO-2016186744-A1 | PROCESS FOR THE MANUFACTURE OF IXABEPILONE | PHARMAREN, LLC (US) | 2016-11-24 | — | — | WO | claimed |
| WO-2024026479-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11873396-B2 | Nanostructures for the assembly of materials | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230346943-A1 | SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-11-02 | — | — | US | disclosed |
| US-20220033639-A1 | NANOSTRUCTURES FOR THE ASSEMBLY OF MATERIALS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-02-03 | — | — | US | disclosed |
| CN-111533675-B | Impurities of heterocyclic boronic acid compounds and methods of controlling the same | 杭州华东医药集团新药研究院有限公司 | 2021-09-28 | — | — | CN | disclosed |
| US-11118048-B2 | Nanostructures for the assembly of materials | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-09-14 | — | — | US | disclosed |
| WO-2021150621-A1 | SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021104355-A1 | IMPURITIES OF HETEROCYCLIC BORONIC ACID COMPOUNDS AND CONTROL METHOD THEREOF | 杭州华东医药集团新药研究院有限公司 | 2021-06-03 | — | — | WO | disclosed |
| US-4254107-A | Long-lasting agonists of enkephalin | MERCK & CO., INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4248868-A | FOR TREATING SYSTEMIC INFECTIONS BY GRAMPOSITIVE AND GRAM NEGATIVE BACTERIA | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4244868-A | Process for the preparation of imidazobenzodiazepines | HOFFMANN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4244867-A | Process for the preparation of imidazobenzodiazepines | HOFFMANN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4226768-A | Process for the preparation of imidazobenzodiazepines | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4166185-A | ANTICONVULSANTS, ANXIOLYTICS, SEDATIVES, MUSCLE RELAXANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-08-28 | — | — | US | disclosed |
| US-4147875-A | ANTIDEPRESSANTS, ANTICONBULSANTS, MUSCLE RELAXANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4146722-A | SEDATIVES, MUSCLE RELAXANTS, ANTICONVULSANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4125726-A | SEDATIVES, MUSCLE RELAXANTS, ANXIOLYTICS, ANTICONVULSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346943-A1 | SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES | DCLRE1A, PCNA, HMBS | DGKA 1247/4885PAM 710/4885TSHR 4246/4885 |
| US-20180072749-A1 | PROCESS FOR THE MANUFACTURE OF IXABEPILONE | SQLE, PPOX, CYP4A11 | DGKA 4442/4885PAM 1144/4885TSHR 500/4885 |
| US-10464942-B2 | Process for the manufacture of ixabepilone | SQLE, PPOX, CYP4A11 | DGKA 4442/4885PAM 1144/4885TSHR 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.