Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | VEGFA | P15692 | 3/20 | 0.38 |
| ▸ | FLT1 | P17948 | 3/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11910920 | 0.76 | KDM4E (0.43) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8947242 | 0.74 | KMT2A (0.67) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL4223717 | 0.70 | MEN1 (0.69) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL13528303 | 0.69 | KDM4E (0.50) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8947150 | 0.69 | GAA (0.67) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL3961994 | 0.69 | GAA (0.59) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL8280364 | 0.69 | GLA (0.63) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL2491198 | 0.68 | HPGD (0.58) | TSHRKMT2AEGLN1GLAPKM | |
| SCHEMBL8957109 | 0.68 | KDM4E (0.61) | KDM4EGAASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL14441183 | 0.68 | RAB9A (0.58) | KDM4EGAASMN1; SMN2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232360-B2 | Stereoregular ROMP polymers | RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20110251363-A1 | STEREOREGULAR ROMP POLYMERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251363-A1 | STEREOREGULAR ROMP POLYMERS | PCBP1, PARG, OSGEP | KDM4E 4097/4885GAA 4055/4885SMN1; SMN2 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.