SCHEMBL3961994

SCHEMBL3961994

COC(=O)CNC(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.59
KDM4E B2RXH2 2/20 0.59
MAPK1 P28482 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
TSHR P16473 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
HSD17B10 Q99714 1/20 0.57
PRSS1 P07477 2/20 0.56
CTSG P08311 2/20 0.56
CTRB1 P17538 2/20 0.56
CMA1 P23946 2/20 0.56
HPGD P15428 1/20 0.56
RAB9A P51151 3/20 0.54
MAPT P10636 1/20 0.54
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
GPR139 Q6DWJ6 1/20 0.53
GLA P06280 1/20 0.52
NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9331679 0.98 GAA (0.57) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL27419582 0.93 GPR139 (0.55) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL29035299 0.93 LMNA (0.55) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL8947242 0.90 KMT2A (0.67) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL5632141 0.90 RAB9A (0.67) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL24224262 0.87 KMT2A (0.59) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL30838576 0.87 KDM4E (0.62) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL8947296 0.87 MMP1 (0.68) GAAKDM4EMAPK1SMN1; SMN2TSHR
SCHEMBL5655365 0.86 PRSS1 (0.68) GAASMN1; SMN2MEN1KMT2APRSS1
SCHEMBL30571840 0.85 KDM4E (0.51) GAAKDM4EMAPK1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425733-A Substance detection method using acylated amino acid hydrolase 学校法人常翔学园 2024-01-19 CN claimed
US-20210101128-A1 SEPARATING COLUMN FOR HIPPURIC ACID ANALYSIS, LIQUID CHROMATOGRAPH FOR HIPPURIC ACID ANALYSIS, AND METHOD FOR ANALYZING HIPPURIC ACID SHIMADZU CORPORATION (JP) 2021-04-08 US claimed
CN-105461705-A Dibenzo-azepine-dione anti-tumor compounds and preparation method thereof UNIV CHINA MEDICAL 2016-04-06 CN claimed
JP-61093956-A None JP disclosed
CN-119684070-A HFIP power assisting C (sp3) Direct methylation method of-H bond and application thereof 西南大学 2025-03-25 CN disclosed
US-12097479-B2 Separating column for separating hippuric acid and mandelic acid, liquid chromatograph for separating hippuric acid and mandelic acid, and method for analyzing hippuric acid and mandelic acid SHIMADZU CORPORATION (JP) 2024-09-24 US disclosed
CN-117946897-A Strain Bacillus velezensis HS-3, culture medium for culturing strain and application of strain 淮南师范学院 2024-04-30 CN disclosed
CN-117897149-A 3, 4-methylenedioxymethamphetamine and related hallucinogens and uses thereof 人类生物科学股份有限公司 2024-04-16 CN disclosed
CN-117425733-A Substance detection method using acylated amino acid hydrolase 学校法人常翔学园 2024-01-19 CN disclosed
US-11767292-B2 Process for making beta 3 agonists and intermediates MERCK SHARP & DOHME CORP. (US) 2023-09-26 US disclosed
US-11767292-B2 Process for making beta 3 agonists and intermediates MERCK SHARP & DOHME CORP. (US) 2023-09-26 US disclosed
CN-1099759-A Piperazine derivatives MERCK PATENT GMBH (DE) 1995-03-08 CN disclosed
EP-0220923-B1 Dipeptides and process GRACE W R & CO (US) 1994-04-27 EP disclosed
EP-0574028-A1 Dipeptide analogs of aspertame and process to prepare them as well as a new preparation of aspertame HAMPSHIRE CHEMICAL CORP. (US) 1993-12-15 EP disclosed
US-4873359-A Process for preparing as partyl-phenylalanine dipeptides W. R. GRACE & CO. - CONN. (US) 1989-10-10 US disclosed
US-4810817-A ARTIFICIAL SWEETENERS W. R. GRACE & CO. (US) 1989-03-07 US disclosed
US-4710583-A ENZYMATIC COUPLING OF PHENYLSERINE WITH ASPARTIC ACID; HYDROGENATION W. R. GRACE & CO. (US) 1987-12-01 US disclosed
EP-0220923-A2 Dipeptides and process W.R. Grace & Co.-Conn. (US) 1987-05-06 EP disclosed
JP-S6193956-A METHOD AND DEVICE FOR ANALYZING VITAL FLUID HITACHI KYOWA KOGYO KK 1986-05-12 JP disclosed
US-4362550-A Herbicidal triazinones ELI LILLY AND COMPANY (US) 1982-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767292-B2 Process for making beta 3 agonists and intermediates ADRB3, ADRB1, ADRB2 GAA 2585/4885KDM4E 4359/4885MAPK1 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.