SCHEMBL11913373

SCHEMBL11913373

O=C(Nc1ccccc1)c1cc2ccccc2c(N=Nc2ccc(-c3nnc(-c4ccc(N=Nc5c(O)c(C(=O)Nc6ccccc6)cc6ccccc56)cc4)o3)cc2)c1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NQO2 P16083 1/20 0.66
▸ MEN1 O00255 5/20 0.51
▸ KMT2A Q03164 5/20 0.51
▸ NPC1 O15118 5/20 0.51
▸ POLB P06746 4/20 0.51
▸ MAPT P10636 4/20 0.51
▸ ALDH1A1 P00352 3/20 0.51
▸ MAPK1 P28482 3/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ IDO1 P14902 1/20 0.51
▸ RECQL P46063 1/20 0.51
▸ CASP6 P55212 1/20 0.51
▸ CTDSP1 Q9GZU7 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ USP2 O75604 2/20 0.50
▸ MITF O75030 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ SMO Q99835 1/20 0.48
▸ RAB9A P51151 4/20 0.47
▸ TSHR P16473 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12677661 0.94 NQO2 (0.62) NQO2MEN1KMT2ANPC1POLB
SCHEMBL14585775 0.90 NQO2 (0.54) NQO2MEN1KMT2ANPC1POLB
SCHEMBL27512683 0.87 NQO2 (0.79) NQO2MEN1KMT2ANPC1POLB
SCHEMBL2630605 0.87 NQO2 (0.79) NQO2MEN1KMT2ANPC1POLB
SCHEMBL11913164 0.87 NQO2 (0.59) NQO2MEN1KMT2ANPC1POLB
SCHEMBL10413849 0.86 NQO2 (0.49) NQO2MEN1KMT2ANPC1POLB
SCHEMBL13707053 0.86 NQO2 (0.52) NQO2MEN1KMT2ANPC1POLB
SCHEMBL1085671 0.84 NQO2 (0.51) NQO2MEN1KMT2ANPC1POLB
SCHEMBL14565033 0.83 NQO2 (0.77) NQO2MEN1KMT2ANPC1POLB
SCHEMBL13111427 0.83 NQO2 (0.80) NQO2MEN1KMT2ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9235145-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2016-01-12 — — US disclosed
US-8951701-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-02-10 — — US disclosed
US-20140321882-A1 COMPOSITION FOR FORMING CHARGE TRANSPORTING FILM, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-10-30 — — US disclosed
US-8808952-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 — — US disclosed
US-8748070-B2 Thiol group-containing charge transporting material, thiol group-containing charge transporting material-dissolving solution, photoelectric conversion device, electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-06-10 — — US disclosed
US-20130260295-A1 COMPOSITION FOR FORMING CHARGE TRANSPORTING FILM, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-10-03 — — US disclosed
US-20120196215-A1 THIOL GROUP-CONTAINING CHARGE TRANSPORTING MATERIAL, THIOL GROUP-CONTAINING CHARGE TRANSPORTING MATERIAL-DISSOLVING SOLUTION, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-08-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120196215-A1 THIOL GROUP-CONTAINING CHARGE TRANSPORTING MATERIAL, THIOL GROUP-CONTAINING CHARGE TRANSPORTING MATERIAL-DISSOLVING SOLUTION, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE SLC9A1, SLC26A3, SLC26A4 NQO2 2302/4885MEN1 2655/4885KMT2A 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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