SCHEMBL11917992

SCHEMBL11917992

NC(c1ccccc1)C(Nc1nc(Cl)nc(C=O)c1Cl)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11918081 0.83 PDE10A (0.34) —
SCHEMBL11903139 0.76 KDM4E (0.36) —
SCHEMBL11918042 0.76 — —
SCHEMBL13769059 0.69 PDE10A (0.34) —
SCHEMBL12738438 0.66 PDE10A (0.38) —
SCHEMBL11918144 0.65 GAA (0.34) —
SCHEMBL12737587 0.64 PDE10A (0.50) —
SCHEMBL14923560 0.62 KHK (0.45) —
SCHEMBL3386362 0.62 KHK (0.45) —
SCHEMBL13731369 0.61 DPP4 (0.50) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120202690-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (US) 2012-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202690-A1 HERBICIDAL COMPOUNDS DDT, HAO2, HAAO DPP4 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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