Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.30 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918081 | 0.87 | PDE10A (0.34) | PDE10AOGG1SLC6A9CCNA2CDK2 | |
| SCHEMBL12738438 | 0.85 | PDE10A (0.38) | PDE10AOGG1CDK7CDK9 | |
| SCHEMBL12737587 | 0.83 | PDE10A (0.50) | PDE10ACDK2 | |
| SCHEMBL12713120 | 0.80 | PDE10A (0.37) | PDE10AAOC3MKNK2MKNK1SLC6A9 | |
| SCHEMBL12713129 | 0.80 | PDE10A (0.37) | PDE10AAOC3MKNK2MKNK1SLC6A9 | |
| SCHEMBL12737608 | 0.73 | PDE10A (0.35) | PDE10AOGG1 | |
| SCHEMBL12738177 | 0.72 | ROCK2 (0.43) | PDE10A | |
| SCHEMBL12738166 | 0.70 | PDE10A (0.35) | PDE10A | |
| SCHEMBL13769322 | 0.70 | ROCK2 (0.36) | PDE10A | |
| SCHEMBL12713170 | 0.69 | PDE10A (0.38) | PDE10ACDK7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |