Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 2/20 | 0.30 |
| ▸ | CDK9 | P50750 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12737587 | 0.88 | PDE10A (0.50) | PDE10AIGF1RMEN1KMT2ALMNA | |
| SCHEMBL13769059 | 0.85 | PDE10A (0.34) | PDE10AOGG1CDK7CDK9 | |
| SCHEMBL11918081 | 0.85 | PDE10A (0.34) | PDE10AOGG1CDK7CDK9 | |
| SCHEMBL12737608 | 0.78 | PDE10A (0.35) | PDE10AOGG1CHRM3PDE4APDE4B | |
| SCHEMBL1609362 | 0.76 | PDE10A (0.40) | PDE10AOGG1S1PR3LPAR2MEN1 | |
| SCHEMBL12712864 | 0.73 | KMT2A (0.40) | PDE10APDE4BPDE4DCNR1MEN1 | |
| SCHEMBL12738147 | 0.73 | PDE10A (0.47) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL12738421 | 0.72 | PDE10A (0.52) | PDE10AOGG1CHRM3PDE4APDE4B | |
| SCHEMBL12738185 | 0.72 | PDE2A (0.35) | PDE10A | |
| SCHEMBL13769322 | 0.71 | ROCK2 (0.36) | PDE10APDE4BPDE4DMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885OGG1 56/4885PDE5A 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.