Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913443 | 0.85 | ADORA2A (0.31) | ADORA2AADORA1MAPTKDM4EMEN1 | |
| SCHEMBL11918051 | 0.81 | DYRK1A (0.38) | — | |
| SCHEMBL11918127 | 0.78 | ALOX5AP (0.32) | — | |
| SCHEMBL10285745 | 0.77 | CRHR1 (0.35) | MAPTTP53MEN1KMT2A | |
| SCHEMBL11918017 | 0.73 | NPSR1 (0.38) | ADORA2AADORA1MEN1POLBKMT2A | |
| SCHEMBL11918099 | 0.73 | MRGPRX1 (0.30) | — | |
| SCHEMBL11913445 | 0.72 | ADORA2A (0.31) | ADORA2AADORA1 | |
| SCHEMBL11918158 | 0.72 | EIF2AK3 (0.32) | — | |
| SCHEMBL11902816 | 0.71 | TAS1R3 (0.37) | ADORA2AADORA1KDM4EGAA | |
| SCHEMBL11918014 | 0.71 | EIF2AK3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | ADORA2A 2029/4885ADORA1 2152/4885MAPT 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.