Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 6/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 6/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LONP1 | P36776 | 6/20 | 0.40 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.40 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921045 | 0.89 | SMN1; SMN2 (0.53) | CNR1SMN1; SMN2ACACBHTTPSMB8 | |
| SCHEMBL464435 | 0.88 | PSMB5 (0.54) | CNR1SMN1; SMN2PSMB8PSMB9PSMB6 | |
| SCHEMBL11920816 | 0.78 | CTSB (0.51) | CNR1SMN1; SMN2ACACBHTTCTSL | |
| SCHEMBL12180708 | 0.77 | PSMB5 (0.53) | CNR1SMN1; SMN2PSMB8PSMB9PSMB6 | |
| SCHEMBL3081564 | 0.77 | PSMB5 (0.53) | CNR1SMN1; SMN2PSMB8PSMB9PSMB6 | |
| SCHEMBL3744717 | 0.76 | PSMB5 (0.68) | PSMB8PSMB9PSMB6PSMB5PSMB10 | |
| SCHEMBL21975356 | 0.75 | CTSL (0.59) | PSMB8PSMB9PSMB6PSMB5PSMB10 | |
| SCHEMBL20095238 | 0.73 | CTSL (0.64) | SMN1; SMN2HTTPSMB8PSMB9PSMB6 | |
| SCHEMBL11933676 | 0.73 | CTSL (0.64) | SMN1; SMN2HTTPSMB8PSMB9PSMB6 | |
| SCHEMBL464428 | 0.72 | LONP1 (0.64) | PSMB8PSMB9PSMB6PSMB5PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212334-B1 | PROTEASOME INHIBITORS | MILLENNIUM PHARM INC (US) | 2012-08-15 | — | — | EP | disclosed |