Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2518981 | 0.92 | TDP1 (0.48) | MAPTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL14118889 | 0.92 | KMT2A (0.58) | MAPTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2518982 | 0.89 | TDP1 (0.45) | MAPTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1673996 | 0.85 | TDP1 (0.47) | MAPTKMT2ATDP1L3MBTL1ATM | |
| SCHEMBL18567268 | 0.85 | TDP1 (0.69) | MAPTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1673995 | 0.85 | TDP1 (0.47) | MAPTKMT2ATDP1L3MBTL1ATM | |
| SCHEMBL2335330 | 0.83 | PTGS2 (0.51) | MAPTKMT2ATDP1ATMHSD17B10 | |
| SCHEMBL28507416 | 0.83 | MAPT (0.56) | MAPTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1191766 | 0.83 | KMT2A (0.42) | MAPTKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL29131366 | 0.82 | KMT2A (0.54) | MAPTKMT2ASMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959873-B1 | GEL COMPOSITION AND METHODS | ALZA CORP (US) | 2006-03-01 | — | — | EP | claimed |
| US-5795695-A | PHOTO-QUALITY RECORDING | XEROX CORPORATION (US) | 1998-08-18 | — | — | US | claimed |
| US-4199517-A | DILVENTS, PLASTICIZERS AND IMPACT MODIFIERS | KENRICH PETROCHEMICALS, INC. (US) | 1980-04-22 | — | — | US | claimed |
| US-11179326-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-10640688-B2 | Adhesive composition, protective film for a polarizing plate, polarizing plate, and liquid crystal display | LG CHEM, LTD. (KR) | 2020-05-05 | — | — | US | disclosed |
| US-20200129425-A1 | SHORT DURATION DEPOT FORMULATIONS | DURECT CORPORATION | 2020-04-30 | — | — | US | disclosed |
| US-10471002-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2019-11-12 | — | — | US | disclosed |
| US-10471001-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190269610-A1 | SHORT DURATION DEPOT FORMULATIONS | DURECT CORP (US) | 2019-09-05 | — | — | US | disclosed |
| US-20190183791-A1 | SHORT DURATION DEPOT FORMULATIONS | DURECT CORP (US) | 2019-06-20 | — | — | US | disclosed |
| US-10201496-B2 | Short duration depot formulations | DURECT CORPORATION (US) | 2019-02-12 | — | — | US | disclosed |
| US-5462993-A | Copolymer of acrylic esters, acrylonitrile, styrene half ester maleate soap, and curing agents for blending with polyvinyl chloride; heat and ultraviolet radiation resistance, artificial leather for automobile interiors | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0669370-A1 | Rubbery blend having low permanent compression set | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5415940-A | Multilayer panel for automobiles with rigid backing, semirigid urethane foams covered with polyvinyl chloride, plasticizer and rubber of addition polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5380785-A | Leathery automotive material: polyvinyl chloride, plasticizer, rubbery polymer of butyl acrylate, at least one of methyl or ethyl /meth/acrylate, acrylonitrile, styrene, crosslinker, half ester maleate soap; emulsion polymerization, seed polymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| US-5362787-A | Rubbery blend having low permanent compression set | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0619328-A1 | Rubbery polymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |
| US-4202810-A | USED AS ACCELERATORS, DILUENTS, PLASTICIZERS | KENRICH PETROCHEMICALS, INC. (US) | 1980-05-13 | — | — | US | disclosed |
| US-4199517-A | DILVENTS, PLASTICIZERS AND IMPACT MODIFIERS | KENRICH PETROCHEMICALS, INC. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4102862-A | Application of cumylphenol and derivatives thereof in plastic compositions | KENRICH PETROCHEMICALS, INC. (US) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10471001-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885KMT2A 4555/4885SMN1; SMN2 3642/4885 |
| US-11179326-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885KMT2A 4555/4885SMN1; SMN2 3642/4885 |
| US-20190183791-A1 | SHORT DURATION DEPOT FORMULATIONS | VEGFA, MMP1, CD44 | MAPT 2866/4885KMT2A 4555/4885SMN1; SMN2 3642/4885 |
| US-10201496-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885KMT2A 4555/4885SMN1; SMN2 3642/4885 |
| US-10471002-B2 | Short duration depot formulations | VEGFA, MMP1, CD44 | MAPT 2866/4885KMT2A 4555/4885SMN1; SMN2 3642/4885 |
| US-20200129425-A1 | SHORT DURATION DEPOT FORMULATIONS | VEGFA, MMP1, CD44 | MAPT 2866/4885KMT2A 4555/4885SMN1; SMN2 3642/4885 |
| US-20190269610-A1 | SHORT DURATION DEPOT FORMULATIONS | VEGFA, MMP1, CD44 | MAPT 2866/4885KMT2A 4555/4885SMN1; SMN2 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.