Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922081 | 0.93 | RXRA (0.38) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL25563043 | 0.92 | KDM4E (0.37) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL21919222 | 0.91 | RXRA (0.41) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL21919153 | 0.90 | BCHE (0.36) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL25563376 | 0.89 | RXRA (0.40) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL25563115 | 0.88 | HSD17B10 (0.33) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL21919154 | 0.88 | KDM4E (0.38) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL23660711 | 0.86 | KDM4E (0.35) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL12116330 | 0.86 | GPR3 (0.39) | RXRARXRBKDM4EHPGDALDH1A1 | |
| SCHEMBL25563152 | 0.86 | GPR3 (0.39) | RXRARXRBKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650565-B2 | Carbazole compound and use thereof | TOSOH CORPORATION (JP) | 2017-05-16 | — | — | US | disclosed |
| US-9650565-B2 | Carbazole compound and use thereof | TOSOH CORPORATION (JP) | 2017-05-16 | — | — | US | disclosed |
| US-20120203010-A1 | CARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2012-08-09 | — | — | US | disclosed |
| US-20120203010-A1 | CARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120203010-A1 | CARBAZOLE COMPOUND AND USE THEREOF | AR, DRD3, AHR | RXRA 568/4885RXRB 589/4885KDM4E 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.