Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21919154 | 0.97 | KDM4E (0.38) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL11922025 | 0.91 | RXRA (0.42) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL21919153 | 0.88 | BCHE (0.36) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL12116329 | 0.84 | GPR3 (0.37) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL12116330 | 0.84 | GPR3 (0.39) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL16786662 | 0.84 | PDK2 (0.37) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL11922081 | 0.84 | RXRA (0.38) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL25563043 | 0.84 | KDM4E (0.37) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL15682255 | 0.84 | KDM4E (0.34) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL12116325 | 0.83 | KDM4E (0.33) | RXRARXRBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186676-B2 | Polymer containing S,S-dioxide-dibenzothiophene in backbone chain with content-adjustable triarylamine end groups and preparation method and application thereof | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2021-11-30 | — | — | US | disclosed |
| US-20200109237-A1 | POLYMER CONTAINING S,S-DIOXIDE-DIBENZOTHIOPHENE IN BACKBONE CHAIN WITH CONTENT-ADJUSTABLE TRIARYLAMINE END GROUPS AND PREPARATION METHOD AND APPLICATION THEREOF | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2020-04-09 | — | — | US | disclosed |