Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.85 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278797 | 0.92 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL18351063 | 0.90 | TAS2R8 (0.86) | TAS2R8TAS2R14 | |
| SCHEMBL1279156 | 0.89 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1279313 | 0.89 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1279276 | 0.89 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1279635 | 0.89 | TAS2R8 (0.85) | TAS2R8TAS2R14 | |
| SCHEMBL11923772 | 0.89 | TAS2R8 (0.85) | TAS2R8TAS2R14 | |
| SCHEMBL1278762 | 0.89 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1278871 | 0.88 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1278938 | 0.88 | TAS2R8 (1.00) | TAS2R8TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487169-A1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | Senomyx Inc. (US) | 2012-08-15 | — | — | EP | disclosed |