Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.86 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278797 | 0.93 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1279635 | 0.92 | TAS2R8 (0.85) | TAS2R8TAS2R14 | |
| SCHEMBL1279313 | 0.92 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL18351058 | 0.91 | TAS2R8 (0.87) | TAS2R8TAS2R14 | |
| SCHEMBL1278938 | 0.90 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL11924099 | 0.90 | TAS2R8 (0.85) | TAS2R8TAS2R14 | |
| SCHEMBL1279156 | 0.90 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1279276 | 0.90 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1278762 | 0.90 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1278871 | 0.89 | TAS2R8 (1.00) | TAS2R8TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | TAS2R8 8/4885TAS2R14 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.