SCHEMBL11926044

SCHEMBL11926044

O=C=Nc1ccc(CC(N=C=O)C(=O)Oc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ PTGS2 P35354 1/20 0.39
▸ LDHA P00338 1/20 0.36
▸ CYP1A2 P05177 1/20 0.35
▸ PPARG P37231 12/20 0.33
▸ PPARA Q07869 11/20 0.33
▸ F2 P00734 1/20 0.32
▸ PRSS1 P07477 1/20 0.32
▸ PRSS2 P07478 1/20 0.32
▸ PRSS3 P35030 1/20 0.32
▸ MIF P14174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11921807 0.92 CYP3A4 (0.37) CYP3A4TSHRPTGS2LDHACYP1A2
SCHEMBL11924843 0.84 MIF (0.46) CYP3A4TSHRLDHACYP1A2PPARG
SCHEMBL28122854 0.81 PPARG (0.40) CYP1A2PPARGPPARAMIF
SCHEMBL15006392 0.81 TSHR (0.50) CYP3A4TSHRPTGS2LDHACYP1A2
SCHEMBL18058731 0.80 CYP3A4 (0.49) CYP3A4TSHRLDHACYP1A2F2
SCHEMBL11908072 0.78 CYP3A4 (0.39) CYP3A4TSHRPTGS2CYP1A2MIF
SCHEMBL11921800 0.78 CYP3A4 (0.34) CYP3A4TSHR
SCHEMBL11906254 0.76 GAA (0.47) CYP3A4TSHR
SCHEMBL15729872 0.75 LDHA (0.53) LDHAPPARGPPARAMIF
SCHEMBL11921801 0.75 CYP3A4 (0.32) CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 — — US disclosed
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 — — US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 — — US disclosed
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
EP-2673259-B1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-04-11 — — EP disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 CYP3A4 1744/4885TSHR 2422/4885PTGS2 1541/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 CYP3A4 2381/4885TSHR 2352/4885PTGS2 1517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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