SCHEMBL11906254

SCHEMBL11906254

O=C=Nc1ccc(CC(NC(=O)c2ccc(N=C=O)cc2)C(=O)Oc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ CTSL P07711 2/20 0.46
▸ PTPN1 P18031 2/20 0.43
▸ CA2 P00918 3/20 0.42
▸ LNPEP Q9UIQ6 1/20 0.41
▸ ITGB3 P05106 1/20 0.40
▸ ITGA2B P08514 1/20 0.40
▸ TMPRSS15 P98073 1/20 0.40
▸ PLG P00747 1/20 0.39
▸ PLAU P00749 1/20 0.39
▸ GPR132 Q9UNW8 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ ACE P12821 1/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CTSB P07858 1/20 0.38
▸ CTSS P25774 1/20 0.38
▸ CTSK P43235 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11926970 0.92 CTSL (0.45) GAARAB9ACTSL
SCHEMBL11921829 0.92 CTSL (0.45) GAARAB9ACTSLPTPN1CA2
SCHEMBL11907538 0.88 GAA (0.55) GAARAB9ACTSLPTPN1CA2
SCHEMBL11921833 0.83 GAA (0.52) GAARAB9ACTSLCA2LNPEP
SCHEMBL12471343 0.83 PTPN1 (0.61) PTPN1CA2ITGB3ITGA2BACE
SCHEMBL22036088 0.82 LNPEP (0.55) GAARAB9ACA2LNPEPTSHR
SCHEMBL11921828 0.81 CA2 (0.56) GAARAB9ACTSLPTPN1CA2
SCHEMBL11926048 0.81 GAA (0.51) GAARAB9ALNPEP
SCHEMBL16846618 0.80 PTPN1 (0.45) GAARAB9ACTSLPTPN1CA2
SCHEMBL16843153 0.78 CTSL (0.42) GAARAB9ACTSLPTPN1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 — — US disclosed
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 — — US disclosed
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 — — US disclosed
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 — — US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 — — US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 — — US disclosed
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
EP-2673259-A2 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM Bezwada Biomedical, LLC (US) 2013-12-18 — — EP disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
WO-2012109535-A2 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-08-16 — — WO disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 GAA 2297/4885RAB9A 3509/4885CTSL 1916/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 GAA 2510/4885RAB9A 3255/4885CTSL 2080/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 GAA 2510/4885RAB9A 3255/4885CTSL 2080/4885
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 GAA 2510/4885RAB9A 3255/4885CTSL 2080/4885
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 GAA 2510/4885RAB9A 3255/4885CTSL 2080/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 GAA 2510/4885RAB9A 3255/4885CTSL 2080/4885
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 GAA 2510/4885RAB9A 3255/4885CTSL 2080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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