Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926959 | 0.85 | FOLH1 (0.44) | NPC1RAB9AKMT2AMAPTL3MBTL1 | |
| SCHEMBL20040445 | 0.82 | KMT2A (0.52) | NPC1RAB9AKMT2AMAPTLMNA | |
| SCHEMBL15006372 | 0.78 | NPC1 (0.50) | NPC1RAB9AKMT2AMAPTLMNA | |
| SCHEMBL5546309 | 0.77 | NAMPT (0.67) | NPC1RAB9AKMT2AL3MBTL1MGLL | |
| SCHEMBL20707157 | 0.77 | NAMPT (0.67) | NPC1RAB9AKMT2AL3MBTL1MGLL | |
| SCHEMBL5515823 | 0.77 | NAMPT (0.67) | NPC1RAB9AKMT2AL3MBTL1MGLL | |
| SCHEMBL5543873 | 0.77 | NAMPT (0.67) | NPC1RAB9AKMT2AL3MBTL1MGLL | |
| SCHEMBL20040443 | 0.76 | NPC1 (0.51) | NPC1RAB9AKMT2AMAPTLMNA | |
| SCHEMBL24112443 | 0.75 | TDP1 (0.65) | KMT2AMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL5536198 | 0.75 | NAMPT (0.64) | NPC1RAB9AKMT2AALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208896-A1 | AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC. (US) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208896-A1 | AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM | SLC7A1, SLC3A2, BCAT2 | NPC1 3612/4885RAB9A 3509/4885KMT2A 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.