Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821668 | 0.88 | RAB9A (0.42) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL10254340 | 0.85 | RAB9A (0.45) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL1276487 | 0.83 | RAB9A (0.46) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL7670563 | 0.83 | PRKCI (0.45) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL28348850 | 0.83 | RAB9A (0.46) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL14015076 | 0.81 | RAB9A (0.44) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL30965 | 0.80 | KDM4E (0.51) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL14000463 | 0.79 | RAB9A (0.43) | RAB9AKDM1AMAOAMAOBNPC1 | |
| SCHEMBL18601204 | 0.78 | ALOX5 (0.44) | RAB9ATAS1R3TAS1R1KDM1AMAOA | |
| SCHEMBL8276391 | 0.76 | CTNNB1 (0.43) | RAB9AKDM1AMAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236815-B2 | Ion channel modulators and methods of uses | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-08-07 | — | — | US | disclosed |