Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10254340 | 0.87 | RAB9A (0.45) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL28348850 | 0.84 | RAB9A (0.46) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL19821668 | 0.83 | RAB9A (0.42) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL11927944 | 0.83 | RAB9A (0.42) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL28133179 | 0.80 | RAB9A (0.39) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL1276487 | 0.78 | RAB9A (0.46) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL30965 | 0.78 | KDM4E (0.51) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL448730 | 0.78 | PRKCI (0.51) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL8276391 | 0.77 | CTNNB1 (0.43) | PRKCIRAB9AKDM1AMAOAMAOB | |
| SCHEMBL14000463 | 0.77 | RAB9A (0.43) | PRKCIRAB9AKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106554350-B | Benzo heterocyclic derivative with beta 2 agonist activity and its prepn and application | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-106554350-A | Benzheterocyclic derivatives with 2 agonist activities of β and its preparation method and application | 四川海思科制药有限公司 | 2017-04-05 | — | — | CN | disclosed |
| US-20020052509-A1 | Calcilytic compounds and method of use | SMITHKLINE BEECHAM CORPORATION | 2002-05-02 | — | — | US | disclosed |
| EP-1069901-A4 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORP (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1069901-A1 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051241-A1 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052509-A1 | Calcilytic compounds and method of use | SOST, CALCR, PTH1R | PRKCI 1048/4885RAB9A 2133/4885KDM1A 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.