SCHEMBL11928871

SCHEMBL11928871

CC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCNC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ MTNR1A P48039 4/20 0.38
▸ MTNR1B P49286 4/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ TSHR P16473 3/20 0.35
▸ CES2 O00748 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ USP2 O75604 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ FAAH O00519 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ NCF1 P14598 1/20 0.33
▸ CA12 O43570 2/20 0.33
▸ CA1 P00915 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13034778 0.96 MEN1 (0.42) MEN1KMT2AMTNR1AMTNR1BMAPK1
SCHEMBL26376485 0.89 CES2 (0.44) MEN1KMT2AKDM4ETSHRCES2
SCHEMBL22856118 0.89 MEN1 (0.47) MEN1KMT2AMTNR1AMTNR1BMAPK1
SCHEMBL13226895 0.89 MEN1 (0.47) MEN1KMT2AMTNR1AMTNR1BMAPK1
SCHEMBL22525359 0.89 MEN1 (0.47) MEN1KMT2AMTNR1AMTNR1BMAPK1
SCHEMBL24509114 0.89 MEN1 (0.47) MEN1KMT2AMTNR1AMTNR1BMAPK1
SCHEMBL12733551 0.88 ALDH1A1 (0.41) MEN1KMT2ATSHRCES2SMN1; SMN2
SCHEMBL7006602 0.88 MEN1 (0.41) MEN1KMT2AKDM4ETSHRCES2
SCHEMBL13040233 0.88 MEN1 (0.41) MEN1KMT2AKDM4ETSHRCES2
SCHEMBL13870367 0.88 MEN1 (0.41) MEN1KMT2AMTNR1AMTNR1BMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247534-B2 Synthesis of radiofluorinated peptide using microwave activation technology GE HEALTHCARE AS (NO) 2012-08-21 — — US disclosed
US-8247534-B2 Synthesis of radiofluorinated peptide using microwave activation technology GE HEALTHCARE AS (NO) 2012-08-21 — — US disclosed
US-8241606-B2 Synthesis of a radiofluorinated peptide using photolabile protecting groups GE HEALTHCARE AS (NO) 2012-08-14 — — US disclosed
US-8241606-B2 Synthesis of a radiofluorinated peptide using photolabile protecting groups GE HEALTHCARE AS (NO) 2012-08-14 — — US disclosed
US-20100022746-A1 SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING PHOTOLABILE PROTECTING GROUPS GE HEALTHCARE AS (NO) 2010-01-28 — — US disclosed
US-20100022746-A1 SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING PHOTOLABILE PROTECTING GROUPS GE HEALTHCARE AS (NO) 2010-01-28 — — US disclosed
US-20100016551-A1 SYNTHESIS OF RADIOFLUORINATED PEPTIDE USING MICROWAVE ACTIVATION TECHNOLOGY GE HEALTHCARE AS (NO) 2010-01-21 — — US disclosed
US-20100016551-A1 SYNTHESIS OF RADIOFLUORINATED PEPTIDE USING MICROWAVE ACTIVATION TECHNOLOGY GE HEALTHCARE AS (NO) 2010-01-21 — — US disclosed
WO-2008075966-A9 SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING PHOTOLABILE PROTECTING GROUPS GE HEALTHCARE AS (NO) 2008-10-30 — — WO disclosed
WO-2008075966-A2 SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING PHOTOLABILE PROTECTING GROUPS GE HEALTHCARE AS (NO) 2008-06-26 — — WO disclosed
WO-2008072976-A2 SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING MICROWAVE ACTIVATION TECHNOLOGY GE HEALTHCARE AS (NO) 2008-06-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022746-A1 SYNTHESIS OF A RADIOFLUORINATED PEPTIDE USING PHOTOLABILE PROTECTING GROUPS QRFPR, DNPEP, VIP MEN1 192/4885KMT2A 2596/4885MTNR1A 946/4885
US-20100016551-A1 SYNTHESIS OF RADIOFLUORINATED PEPTIDE USING MICROWAVE ACTIVATION TECHNOLOGY VIP, QRFPR, GRPR MEN1 18/4885KMT2A 2669/4885MTNR1A 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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