Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11928874 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL13113388 | 0.97 | CES2 (0.42) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL13014736 | 0.96 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL72044 | 0.93 | CES2 (0.42) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL13154532 | 0.90 | CES2 (0.42) | ALDH1A1TSHRMEN1KMT2AEPHX2 | |
| SCHEMBL23518687 | 0.89 | MEN1 (0.46) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL25516086 | 0.89 | MEN1 (0.46) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL25028599 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL15335399 | 0.88 | MEN1 (0.45) | ALDH1A1TSHRMEN1KMT2ACES2 | |
| SCHEMBL11928871 | 0.88 | MEN1 (0.42) | ALDH1A1TSHRMEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150633-B2 | Insulin analogues with an acyl and alkylene glycol moiety | NOVO NORDISK A/S (DK) | 2015-10-06 | — | — | US | disclosed |
| US-8444955-B2 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-20110098440-A1 | Insulin Analogues with an Acyl and Alkylene Glycol Moiety | NOVO NORDISK A/S (DK) | 2011-04-28 | — | — | US | disclosed |
| US-20100196270-A1 | RADIOFLUORINATION METHODS | GE HEALTHCARE AS (NO) | 2010-08-05 | — | — | US | disclosed |
| US-7591994-B2 | Improved targetting | IMMUNOMEDICS, INC. (US) | 2009-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098440-A1 | Insulin Analogues with an Acyl and Alkylene Glycol Moiety | IAPP, INSR, IGF1R | ALDH1A1 4291/4885TSHR 372/4885THRB 438/4885 |
| US-20100196270-A1 | RADIOFLUORINATION METHODS | CYP2F1, CYP4F2, CYP4F3 | ALDH1A1 534/4885TSHR 132/4885THRB 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.