Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.66 |
| ▸ | TUBB | P07437 | 4/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.66 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.66 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.66 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.66 |
| ▸ | MET | P08581 | 2/20 | 0.66 |
| ▸ | CDK9 | P50750 | 2/20 | 0.66 |
| ▸ | KDR | P35968 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Luxabendazole SCHEMBL321908 | 0.99 | TUBB4A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Luxabendazole SCHEMBL6055930 | 0.91 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Luxabendazole SCHEMBL29765623 | 0.91 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11868259 | 0.90 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11868920 | 0.89 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5036244 | 0.89 | MET (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11878160 | 0.88 | TUBB4A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11870396 | 0.88 | TUBB4A (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14300495 | 0.88 | TUBB4A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5033395 | 0.87 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893271-B2 | Benzimidazole carbamates and (thio) carbamates, and the synthesis and use thereof | INTERVET INTERNATIONAL B.V. (NL) | 2011-02-22 | — | — | US | disclosed |
| EP-1913009-B1 | NOVEL BENZIMIDAZOLE (THIO) CARBAMATES WITH ANTIPARASITIC ACTIVITY AND THE SYNTHESIS THEREOF | INTERVET INT BV (NL) | 2010-05-12 | — | — | EP | disclosed |
| US-20090131369-A1 | Novel Benzimidazole(Thio)Carbamates with Antiparasitic Activity and the Synthesis Thereof | INTERVET INTERNATIONAL B.V. (NL) | 2009-05-21 | — | — | US | disclosed |
| EP-1913009-A1 | NOVEL BENZIMIDAZOLE (THIO) CARBAMATES WITH ANTIPARASITIC ACTIVITY AND THE SYNTHESIS THEREOF | Intervet International BV (NL) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007014846-A1 | NOVEL BENZIMIDAZOLE (THIO) CARBAMATES WITH ANTIPARASITIC ACTIVITY AND THE SYNTHESIS THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131369-A1 | Novel Benzimidazole(Thio)Carbamates with Antiparasitic Activity and the Synthesis Thereof | CYP2C8, CYP3A7, CYP8B1 | TUBB4A 558/4885TUBB 280/4885TUBA3C 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.