SCHEMBL11938313

SCHEMBL11938313

Cc1ccc(CCC(=O)c2c(O)cc(O)cc2OC2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

nearest known ligand 0.87

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 16/20 0.87
▸ SLC5A2 P31639 8/20 0.87
▸ HPGD P15428 2/20 0.87
▸ HSD17B10 Q99714 2/20 0.87
▸ SLC28A3 Q9HAS3 2/20 0.87
▸ KDM4E B2RXH2 1/20 0.87
▸ CYP3A4 P08684 1/20 0.87
▸ MAPT P10636 1/20 0.87
▸ THRB P10828 1/20 0.87
▸ CYP2C9 P11712 1/20 0.87
▸ CYP2C19 P33261 1/20 0.87
▸ SLC28A2 O43868 1/20 0.87
▸ EPHX2 P34913 1/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18326539 1.00 SLC5A1 (0.87) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL113699 0.93 SLC5A1 (1.00) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL18058585 0.93 SLC5A1 (1.00) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL17290 0.93 SLC5A1 (1.00) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL2826870 0.93 SLC5A1 (1.00) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL23802544 0.93 SLC5A1 (1.00) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL16421567 0.93 SLC5A1 (1.00) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL22022720 0.93 SLC5A1 (1.00) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL7647026 0.92 SLC5A1 (0.98) SLC5A1SLC5A2HPGDHSD17B10SLC28A3
Phlorizin SCHEMBL28823647 0.92 SLC5A1 (0.98) SLC5A1SLC5A2HPGDHSD17B10SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 — — US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 SLC5A1 3886/4885SLC5A2 3603/4885HPGD 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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